欧美日韩三区四区_试看120秒一区二区三区_亚洲一区二区在线观看视频_久久综合色88

今天是2025年8月6日 星期三,歡迎光臨本站 上海研生實業有限公司 網址: www.845158.com

一抗

膽綠素還原酶抗體

文字:[大][中][小] 2017-5-4    瀏覽次數:1488    

英文名稱 Anti-BLVRA/Biliverdin Reductase
中文名稱: 膽綠素還原酶抗體
別 名 Biliverdin IX alpha reductase; Biliverdin reductase A; BLVR A; BLVR; BLVRA; BVR A; BVR; BVRA; zinc-metalloprotein; BIEA_HUMAN.

詳細介紹:


濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Pig
產品類型 一抗
研究領域 細胞生物 免疫學 信號轉導 激酶和磷酸酶 新陳代謝
蛋白分子量 predicted molecular weight: 33kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BLVRA/Biliverdin Reductase
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

相關資料:


產品介紹 In human liver cytosolic fractions, four forms of biliverdin reductase have been identified, including two biliverdin-IX Beta reductases and two biliverdin-IX Alpha reductases, designated isozymes I and II and isozymes III and IV, respectively. Biliverdin reductase A (BLVRA), also designated biliverdin-IX Alpha-reductase, belongs to the GFO/iIDH/MocA family and the biliverdin reductase subfamily. The gene that encodes this cytoplasmic protein maps to chromosome 7p14-cen. BLVRA reduces biliverdin IX (the methene bridge of the open tetrapyrrole) to bilirubin with the concomitant oxidation of an NADH or NADPH cofactor (bilirubin + NADP+ = biliverdin + NADPH). BLVRA is expressed primarily in liver.
Function : Biliverdin Reductase (BVR) catalyzes the final step in the heme metabolic pathway, the reduction of biliverdin IX{alpha} to bilirubin, with the concomitant oxidation of a NADH or NADPH cofactor. The enzyme remains unique among all biological catalysts described to date in having a dual pH/cofactor-dependent activity profile. Human biliverdin reductase (hBVR) has been recently shown to be a Ser/Thr/Tyr kinase in the MAPK insulin/insulin-like growth factor 1 (IGF1)-signaling cascade. BVR together with its substrate, biliverdin, and product, bilirubin, have recently been revealed to be important players in cellular signal transduction pathways, gene expression and oxidative response. These features make BVR unusually interesting and unique among all enzymes characterized to date.
Subunit : Monomer.
Subcellular Location : Cytoplasmic
Tissue Specificity : Liver.
DISEASE : Defects in BLVRA are the cause of hyperbiliverdinemia(HBLVD) [MIM:614156]. HBLVD is a condition characterized by a greendiscoloration of the skin, urine, serum, and other bodily fluids.It is due to increased biliverdin resulting from inefficientconversion to bilirubin. Affected individuals appear to havesymptoms only in the context of obstructive cholestasis and/orliver failure. In some cases, green jaundice can resolve afterresolution of obstructive cholestasis.
Similarity : Belongs to the Gfo/Idh/MocA family. Biliverdinreductase subfamily.
Database links : UniProtKB/Swiss-Prot: P53004.2


返回上一步
打印此頁
[向上]

網站首頁

公司介紹

產品中心

技術服務

技術文獻

在線留言

聯系我們

Adodb 數據庫操作失敗Adodb 關閉數據庫連接失敗 主站蜘蛛池模板: 泾川县| 会昌县| 栾川县| 汨罗市| 保亭| 南宁市| 墨玉县| 翁牛特旗| 临澧县| 景洪市| 藁城市| 左贡县| 兰考县| 万全县| 图木舒克市| 寿光市| 久治县| 泰和县| 大邑县| 西平县| 民乐县| 石台县| 张家界市| 福泉市| 永善县| 轮台县| 花莲县| 隆德县| 浏阳市| 昌乐县| 娱乐| 都匀市| 甘德县| 汉阴县| 来安县| 余姚市| 台中县| 西和县| 肇东市| 沙河市| 武穴市|