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釉基質(zhì)蛋白抗體

文字:[大][中][小] 2017-5-4    瀏覽次數(shù):1393    

                                                       釉基質(zhì)蛋白抗體                                                                                                                                                
英文名稱  Anti-AMBN 
中文名稱  釉基質(zhì)蛋白抗體 
別    名  AMBN; AMBN_HUMAN; Ameloblastin (enamel matrix protein); Ameloblastin. 

詳細介紹:


濃    度  1mg/1ml 
規(guī) 格  0.2ml/200μg   
抗體來源  Rabbit  
克隆類型  polyclonal 
交叉反應(yīng)  Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
產(chǎn)品類型  一抗    
研究領(lǐng)域  細胞生物 信號轉(zhuǎn)導 細胞骨架 細胞外基質(zhì)  
蛋白分子量  predicted molecular weight: 45kDa 
性    狀  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human AMBN 
亞    型  IgG 
純化方法  affinity purified by Protein A 
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
(石蠟切片需做抗原修復) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

相關(guān)資料:


產(chǎn)品介紹 Dental enamel is a highly mineralized tissue with most of its volume occupied by large, highly organized, hydroxyapatite crystals. This structure is thought to be controlled through the interaction of many organic matrix molecules including amelogenin, ameloblastin, enamelin, tuftelin and several other enzymes. All of these secreted proteins are involved in the mineralization and enamel matrix formation in developing tooth enamel. Ameloblastin (AMBN), which localizes to the extracellular matrix, is an ameloblast-specific protein. It is detected in the sheath space between rod-interrod enamel and at the Tomes processes of secretory ameloblasts. Defects in the gene encoding for ameloblastin, AMBN, can be seen in patients with ameloblastomas.
Function : Involved in the mineralization and structural organization of enamel.
Subcellular Location : Secreted > extracellular space > extracellular matrix.
Tissue Specificity : Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.
Similarity : Belongs to the ameloblastin family.
Database links : UniProtKB/Swiss-Prot: Q9NP70.1

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