欧美日韩三区四区_试看120秒一区二区三区_亚洲一区二区在线观看视频_久久综合色88

今天是2025年8月8日 星期五,歡迎光臨本站 上海研生實業有限公司 網址: www.845158.com

標記一抗

FITC標記的酪氨酸蛋白激酶BTK抗

文字:[大][中][小] 2017-5-3    瀏覽次數:1227    

                                   FITC標記的酪氨酸蛋白激酶BTK抗                                                                                                                                                
英文名稱Anti-ATK/BTK/FITC
中文名稱:FITC標記的酪氨酸蛋白激酶BTK抗體
別    名Agammaglobulinaemia tyrosine kinase; AGMX 1; AGMX1; AT; ATK; B cell progenitor kinase; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton’s Tyrosine Kinase; Btk; BTK_HUMAN; IMD 1; IMD1; MGC126261; MGC126262; OTTHUMP00000063593; PSCTK 1; PSCTK1; Tyrosine protein kinase BTK; Tyrosine-protein kinase BTK; XLA.  

詳細介紹:


規格:100ul 
說 明 書100ul  
研究領域激酶和磷酸酶  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
產品應用IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量76kDa
細胞定位細胞膜 
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human BTK
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關資料:


產品介紹background:
Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

返回上一步
打印此頁
[向上]

網站首頁

公司介紹

產品中心

技術服務

技術文獻

在線留言

聯系我們

在線客服

售前咨詢

售后服務

咨詢電話:
021-59989018

請掃描二維碼
打開手機站

主站蜘蛛池模板: 四会市| 锡林郭勒盟| 正宁县| 井研县| 运城市| 隆昌县| 萍乡市| 大庆市| 长治市| 连平县| 开原市| 海口市| 黄大仙区| 永修县| 田林县| 瓦房店市| 江山市| 仪陇县| 上蔡县| 东乡族自治县| 临沂市| 尼勒克县| 门源| 三江| 易门县| 南宁市| 墨竹工卡县| 高青县| 奉贤区| 河北区| 七台河市| 繁昌县| 彰武县| 合水县| 平湖市| 咸阳市| 乌拉特前旗| 六盘水市| 武穴市| 手游| 雷州市|