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膜粘連蛋白11抗體

文字:[大][中][小] 2017-5-4    瀏覽次數:1314    

                                                       膜粘連蛋白11抗體                                                                                                                                                
英文名稱  Anti-Annexin A11 
中文名稱  膜粘連蛋白11抗體 
別    名  56 kDa autoantigen; Annexin A11; Annexin XI; Annexin-11; AnnexinA11; AnnexinXI; ANX 11; ANX A11; ANX11; ANX11_HUMAN; ANXA 11; ANXA11; Autoantigen 56 kD; Calcyclin associated annexin 50; Calcyclin-associated annexin 50; CAP 50; CAP-50; CAP50; OTTHUMP00000059806. 

詳細介紹:


濃    度  1mg/1ml 
規 格  0.2ml/200μg  
抗體來源  Rabbit  
克隆類型  polyclonal 
交叉反應  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep   
產品類型  一抗    
研究領域  細胞生物 信號轉導 通道蛋白 細胞粘附分子 細胞膜蛋白  
蛋白分子量  predicted molecular weight: 54kDa 
性    狀  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human Annexin A11 
亞    型  IgG 
純化方法  affinity purified by Protein A 
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
產品應用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
(石蠟切片需做抗原修復) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

相關資料:


產品介紹 The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca2+-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
Function : Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.
Subunit : Interacts with S100A6 (By similarity). Interacts with PDCD6 in a calcium-dependent manner. Interacts with KIF23 during cytokinesis. 
Subcellular Location : Cytoplasm. Melanosome. Nucleus envelope. Nucleus > nucleoplasm. Cytoplasm > cytoskeleton > spindle. Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope, with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent.
Similarity : Belongs to the annexin family.
Contains 4 annexin repeats.
Database links : UniProtKB/Swiss-Prot: P50995.1

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