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FITC標記的Rho GTP酶激活蛋白24抗體

文字:[大][中][小] 2017-5-3    瀏覽次數:1141    

                                   FITC標記的Rho GTP酶激活蛋白24抗體                                                                                                                                                
英文名稱Anti-ARHGAP24/FITC
中文名稱:FITC標記的Rho GTP酶激活蛋白24抗體
別    名ARHGAP24; Filamin A associated RhoGAP; FILGAP; p73; p73RhoGAP; RAC1 and CDC4 specific GTPase activating protein of 72kDa; RCGAP72; Rho GTPase activating protein 24; Rho type GTPase activating protein 24; Rho GTPase-activating protein 24; RhoGAP of 73 kDa; Sarcoma antigen NY SAR 88; RHG24_HUMAN.  

詳細介紹:


規格:100ul 
說 明 書100ul  
研究領域腫瘤  免疫學  信號轉導  生長因子和激素  G蛋白偶聯受體  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Dog, Pig, Cow, Horse, Sheep, 
產品應用IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量84kDa
細胞定位細胞膜 
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ARHGAP24 (631-680aa)
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關資料:


產品介紹background:
ARHGAP24 is a rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. It acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. It controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. There are five different isoforms.Isoform 1 is widely expressed with a higher level in kidney. Isoform 2 is mainly expressed in endothelial cells and is involved in modulation of angiogenesis.

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