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FITC標記的β淀粉樣蛋白前體蛋白結合蛋白2抗體

文字:[大][中][小] 2017-5-2    瀏覽次數:1145    

                         FITC標記的β淀粉樣蛋白前體蛋白結合蛋白2抗體                                                                                                                                               
英文名稱Anti-APPBP2/FITC
中文名稱:FITC標記的β淀粉樣蛋白前體蛋白結合蛋白2抗體
別    名amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interacting with APP tail 1.  

詳細介紹:


規格:100ul 
說 明 書100ul  
研究領域免疫學  神經生物學  Alzheimer's  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish, 
產品應用ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量67kDa
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human APPBP2
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關資料:


產品介紹background:
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008

Function:
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Subunit:
Binds APP. 

Subcellular Location:
Nucleus. Cytoplasm

Post-translational modifications:
Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.

Similarity:
Contains 8 TPR repeats.

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